Compounded Tirzepatide 14 mg (Sublingual) 14.29 mg / 0.5 mL — Compounded Sublingual Liquid Patient Monograph
Patient education monograph for Compounded Tirzepatide 14 mg (Sublingual) (14.29 mg / 0.5 mL), a compounded sublingual liquid. Learn how it works, how to use it, possible side effects, and find a licensed compounding pharmacy near you.
What is Compounded Tirzepatide 14 mg (Sublingual)?
This compounded preparation contains tirzepatide 14.29 mg per 0.5 mL in a sublingual liquid base, prepared by a licensed compounding pharmacy pursuant to a valid individual patient prescription. It represents an advanced maintenance dose for patients who have titrated through lower tirzepatide doses and are continuing a medically supervised weight management program. Compounded tirzepatide is not an FDA-approved product. Formula developed in partnership with Richie's Specialty Pharmacy.
How does Compounded Tirzepatide 14 mg (Sublingual) work?
Tirzepatide exerts dual agonist activity at GIP and GLP-1 receptors, producing additive and synergistic effects on appetite suppression, gastric motility, and insulin secretion. At 14.29 mg per weekly dose, the preparation delivers near-maximal GIP and GLP-1 receptor engagement, supporting sustained appetite control and weight maintenance. The sublingual formulation is designed to facilitate mucosal peptide absorption as an alternative to subcutaneous injection.
How to use Compounded Tirzepatide 14 mg (Sublingual)
Administer under the tongue once weekly as prescribed. Hold the preparation under the tongue for at least 60 seconds before swallowing. Avoid eating, drinking, or rinsing your mouth for at least 10 minutes after administration. Use on the same scheduled day each week. Do not modify the dose or schedule without your prescriber's guidance.
Compounded Tirzepatide 14 mg (Sublingual) side effects
Nausea, vomiting, constipation, diarrhea, and reduced appetite are expected at this dose level. GI side effects may be more pronounced than at lower doses, particularly if recently escalated. Fatigue, dizziness, and mild hair loss (related to rapid weight loss) may occur. Gallbladder disease risk is elevated with significant weight loss — report any upper right abdominal pain. Report severe GI distress or signs of pancreatitis immediately.
Drug interactions with Compounded Tirzepatide 14 mg (Sublingual)
Tirzepatide delays gastric emptying — allow additional time between this preparation and oral drugs where absorption timing is critical. Concurrent insulin or sulfonylurea use requires monitoring for hypoglycemia. Report all medications and supplements to your prescriber, particularly narrow therapeutic window drugs (anticoagulants, thyroid medications, antiepileptics).
How to store Compounded Tirzepatide 14 mg (Sublingual)
Refrigerate at 36°F–46°F (2°C–8°C). Do not freeze. Protect from light. Keep tightly closed. Use within the beyond-use date printed on the label. Discard any solution that appears cloudy or discolored.
Precautions for Compounded Tirzepatide 14 mg (Sublingual)
Contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia type 2. At this dose, careful prescriber supervision is essential. Gallbladder complications associated with rapid weight loss are a known risk — discuss with your prescriber. Use only under active medical supervision. Keep out of reach of children.
Frequently Asked Questions — Compounded Tirzepatide 14 mg (Sublingual)
- What is Compounded Tirzepatide 14 mg (Sublingual)?
- This compounded preparation contains tirzepatide 14.29 mg per 0.5 mL in a sublingual liquid base, prepared by a licensed compounding pharmacy pursuant to a valid individual patient prescription. It represents an advanced maintenance dose for patients who have titrated through lower tirzepatide doses and are continuing a medically supervised weight management program. Compounded tirzepatide is not an FDA-approved product. Formula developed in partnership with Richie's Specialty Pharmacy.
- How does Compounded Tirzepatide 14 mg (Sublingual) work?
- Tirzepatide exerts dual agonist activity at GIP and GLP-1 receptors, producing additive and synergistic effects on appetite suppression, gastric motility, and insulin secretion. At 14.29 mg per weekly dose, the preparation delivers near-maximal GIP and GLP-1 receptor engagement, supporting sustained appetite control and weight maintenance. The sublingual formulation is designed to facilitate mucosal peptide absorption as an alternative to subcutaneous injection.
- How do I use Compounded Tirzepatide 14 mg (Sublingual)?
- Administer under the tongue once weekly as prescribed. Hold the preparation under the tongue for at least 60 seconds before swallowing. Avoid eating, drinking, or rinsing your mouth for at least 10 minutes after administration. Use on the same scheduled day each week. Do not modify the dose or schedule without your prescriber's guidance.
- What are the side effects of Compounded Tirzepatide 14 mg (Sublingual)?
- Nausea, vomiting, constipation, diarrhea, and reduced appetite are expected at this dose level. GI side effects may be more pronounced than at lower doses, particularly if recently escalated. Fatigue, dizziness, and mild hair loss (related to rapid weight loss) may occur. Gallbladder disease risk is elevated with significant weight loss — report any upper right abdominal pain. Report severe GI distress or signs of pancreatitis immediately.
- Are there drug interactions with Compounded Tirzepatide 14 mg (Sublingual)?
- Tirzepatide delays gastric emptying — allow additional time between this preparation and oral drugs where absorption timing is critical. Concurrent insulin or sulfonylurea use requires monitoring for hypoglycemia. Report all medications and supplements to your prescriber, particularly narrow therapeutic window drugs (anticoagulants, thyroid medications, antiepileptics).
- How should I store Compounded Tirzepatide 14 mg (Sublingual)?
- Refrigerate at 36°F–46°F (2°C–8°C). Do not freeze. Protect from light. Keep tightly closed. Use within the beyond-use date printed on the label. Discard any solution that appears cloudy or discolored.
- What precautions should I know about Compounded Tirzepatide 14 mg (Sublingual)?
- Contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia type 2. At this dose, careful prescriber supervision is essential. Gallbladder complications associated with rapid weight loss are a known risk — discuss with your prescriber. Use only under active medical supervision. Keep out of reach of children.
- Where can I get compounded Compounded Tirzepatide 14 mg (Sublingual)?
- Compounded Tirzepatide 14 mg (Sublingual) is available through licensed compounding pharmacies on the SlimionRX network. Visit slimionrx.com to find a pharmacy near you.