Sermorelin Per prescriber order — Compounded Subcutaneous Injection Patient Monograph
Patient education monograph for Sermorelin (Per prescriber order), a compounded subcutaneous injection. Learn how it works, how to use it, possible side effects, and find a licensed compounding pharmacy near you.
What is Sermorelin?
This compounded preparation contains sermorelin, a synthetic growth hormone-releasing hormone (GHRH) analogue, prepared pursuant to an individual patient prescription. Sermorelin was previously approved in the United States for diagnostic evaluation of growth hormone deficiency but is not currently marketed as an FDA-approved drug product. Compounded sermorelin preparations may be prepared by pharmacies pursuant to a valid prescription.
How does Sermorelin work?
Sermorelin binds to GHRH receptors in the anterior pituitary gland, stimulating the pulsatile release of your body's own natural growth hormone — rather than introducing exogenous GH directly. This preserves the body's natural feedback regulation. Increased growth hormone levels may lead to increased circulating insulin-like growth factor-1 (IGF-1), which mediates many of growth hormone's anabolic and metabolic effects.
How to use Sermorelin
Administer subcutaneously as directed by your prescriber, typically at bedtime on an empty stomach. Follow your pharmacist's reconstitution instructions carefully. Administration schedule should follow the prescribing provider's instructions.
Sermorelin side effects
Injection site reactions, flushing, headache, and dizziness may occur. Water retention (swelling in hands or feet) and joint pain have been reported at higher doses. These effects often improve with dose adjustment. Contact your prescriber if symptoms are persistent or severe.
Drug interactions with Sermorelin
May interact with glucocorticoids (corticosteroids), thyroid hormones, and insulin. Certain medications affecting pituitary function may reduce sermorelin's effectiveness. Inform your prescriber of all medications and supplements you are taking.
How to store Sermorelin
Store the lyophilized (freeze-dried) powder refrigerated at 2–8°C (36–46°F). Protect from light. Do not freeze. After reconstitution, refrigerate and use within the timeframe specified by your pharmacy. Discard if the solution appears discolored or contains visible particulate matter.
Precautions for Sermorelin
Do not use if you have active cancer without prescriber guidance. May affect glucose metabolism — use with caution if you have diabetes or blood sugar concerns. Safety during pregnancy and breastfeeding has not been established; inform your prescriber if you are pregnant or planning to become pregnant. Report headaches, significant water retention, or joint pain to your prescriber. Keep out of rea
Frequently Asked Questions — Sermorelin
- What is Sermorelin?
- This compounded preparation contains sermorelin, a synthetic growth hormone-releasing hormone (GHRH) analogue, prepared pursuant to an individual patient prescription. Sermorelin was previously approved in the United States for diagnostic evaluation of growth hormone deficiency but is not currently marketed as an FDA-approved drug product. Compounded sermorelin preparations may be prepared by pharmacies pursuant to a valid prescription.
- How does Sermorelin work?
- Sermorelin binds to GHRH receptors in the anterior pituitary gland, stimulating the pulsatile release of your body's own natural growth hormone — rather than introducing exogenous GH directly. This preserves the body's natural feedback regulation. Increased growth hormone levels may lead to increased circulating insulin-like growth factor-1 (IGF-1), which mediates many of growth hormone's anabolic and metabolic effects.
- How do I use Sermorelin?
- Administer subcutaneously as directed by your prescriber, typically at bedtime on an empty stomach. Follow your pharmacist's reconstitution instructions carefully. Administration schedule should follow the prescribing provider's instructions.
- What are the side effects of Sermorelin?
- Injection site reactions, flushing, headache, and dizziness may occur. Water retention (swelling in hands or feet) and joint pain have been reported at higher doses. These effects often improve with dose adjustment. Contact your prescriber if symptoms are persistent or severe.
- Are there drug interactions with Sermorelin?
- May interact with glucocorticoids (corticosteroids), thyroid hormones, and insulin. Certain medications affecting pituitary function may reduce sermorelin's effectiveness. Inform your prescriber of all medications and supplements you are taking.
- How should I store Sermorelin?
- Store the lyophilized (freeze-dried) powder refrigerated at 2–8°C (36–46°F). Protect from light. Do not freeze. After reconstitution, refrigerate and use within the timeframe specified by your pharmacy. Discard if the solution appears discolored or contains visible particulate matter.
- What precautions should I know about Sermorelin?
- Do not use if you have active cancer without prescriber guidance. May affect glucose metabolism — use with caution if you have diabetes or blood sugar concerns. Safety during pregnancy and breastfeeding has not been established; inform your prescriber if you are pregnant or planning to become pregnant. Report headaches, significant water retention, or joint pain to your prescriber. Keep out of rea
- Where can I get compounded Sermorelin?
- Sermorelin is available through licensed compounding pharmacies on the SlimionRX network. Visit slimionrx.com to find a pharmacy near you.