Compounded Semaglutide 3 mg (Sublingual) 3.05 mg / 0.5 mL — Compounded Sublingual Liquid Patient Monograph

Patient education monograph for Compounded Semaglutide 3 mg (Sublingual) (3.05 mg / 0.5 mL), a compounded sublingual liquid. Learn how it works, how to use it, possible side effects, and find a licensed compounding pharmacy near you.

What is Compounded Semaglutide 3 mg (Sublingual)?

This compounded preparation contains semaglutide 3.05 mg in a 0.5 mL sublingual liquid base, prepared by a licensed compounding pharmacy pursuant to a valid individual patient prescription. It is designed as an introductory or low-dose option within a medically supervised weight management program. Compounded semaglutide is not an FDA-approved product and is prepared under a prescriber's order for a specific patient. Formula developed in partnership with Richie's Specialty Pharmacy.

How does Compounded Semaglutide 3 mg (Sublingual) work?

Semaglutide is a GLP-1 receptor agonist that mimics glucagon-like peptide-1, a hormone released from the gut after eating. It acts on receptors in the brain's appetite centers to reduce hunger signals, slows gastric emptying to prolong satiety, and stimulates insulin release from the pancreas in response to elevated blood glucose. At the 3.05 mg sublingual dose, it provides GLP-1 receptor engagement suitable for initiation and early titration, minimizing GI side effects while establishing therapeutic effect.

How to use Compounded Semaglutide 3 mg (Sublingual)

Place the prescribed dose under the tongue as directed by your prescriber. Hold the preparation in place for at least 60 seconds before swallowing. Do not eat, drink, or rinse your mouth for at least 10 minutes after administration. Use on the same day each week. Follow your prescriber's titration schedule precisely — do not increase the dose on your own.

Compounded Semaglutide 3 mg (Sublingual) side effects

Nausea, decreased appetite, mild constipation, and loose stools are the most commonly reported effects, especially during the first few weeks of therapy. These effects are generally dose-related and improve as the body adjusts. Headache and mild fatigue may also occur. At this introductory dose, GI effects are typically less pronounced than at higher doses. Report any severe abdominal pain, persistent vomiting, or signs of dehydration to your prescriber promptly.

Drug interactions with Compounded Semaglutide 3 mg (Sublingual)

Semaglutide slows gastric emptying and may delay absorption of other oral medications — leave additional time between this preparation and other drugs taken by mouth. Concurrent use with insulin or sulfonylureas increases hypoglycemia risk; dose adjustment of those agents may be necessary. Inform your prescriber of all medications, including thyroid drugs, blood thinners, and over-the-counter preparations.

How to store Compounded Semaglutide 3 mg (Sublingual)

Refrigerate at 36°F–46°F (2°C–8°C). Do not freeze. Protect from light. Keep tightly closed. Use within the beyond-use date printed on the pharmacy label. Do not use if the solution appears cloudy, discolored, or contains visible particles.

Precautions for Compounded Semaglutide 3 mg (Sublingual)

Do not use if you have a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. Notify your prescriber immediately of any severe abdominal pain, persistent nausea, or signs of an allergic reaction. Use only under direct prescriber supervision as part of a comprehensive weight management program. Keep out of reach of children.

Where to get compounded Compounded Semaglutide 3 mg (Sublingual)

Compounded Semaglutide 3 mg (Sublingual) is available through licensed compounding pharmacies on the SlimionRX network:

Benbrook pharmacy — Benbrook, TX
Lux Med Compounding Pharmacy — Lewisville, TX

Frequently Asked Questions — Compounded Semaglutide 3 mg (Sublingual)

What is Compounded Semaglutide 3 mg (Sublingual)?: This compounded preparation contains semaglutide 3.05 mg in a 0.5 mL sublingual liquid base, prepared by a licensed compounding pharmacy pursuant to a valid individual patient prescription. It is designed as an introductory or low-dose option within a medically supervised weight management program. Compounded semaglutide is not an FDA-approved product and is prepared under a prescriber's order for a specific patient. Formula developed in partnership with Richie's Specialty Pharmacy.
How does Compounded Semaglutide 3 mg (Sublingual) work?: Semaglutide is a GLP-1 receptor agonist that mimics glucagon-like peptide-1, a hormone released from the gut after eating. It acts on receptors in the brain's appetite centers to reduce hunger signals, slows gastric emptying to prolong satiety, and stimulates insulin release from the pancreas in response to elevated blood glucose. At the 3.05 mg sublingual dose, it provides GLP-1 receptor engagement suitable for initiation and early titration, minimizing GI side effects while establishing therap
How do I use Compounded Semaglutide 3 mg (Sublingual)?: Place the prescribed dose under the tongue as directed by your prescriber. Hold the preparation in place for at least 60 seconds before swallowing. Do not eat, drink, or rinse your mouth for at least 10 minutes after administration. Use on the same day each week. Follow your prescriber's titration schedule precisely — do not increase the dose on your own.
What are the side effects of Compounded Semaglutide 3 mg (Sublingual)?: Nausea, decreased appetite, mild constipation, and loose stools are the most commonly reported effects, especially during the first few weeks of therapy. These effects are generally dose-related and improve as the body adjusts. Headache and mild fatigue may also occur. At this introductory dose, GI effects are typically less pronounced than at higher doses. Report any severe abdominal pain, persistent vomiting, or signs of dehydration to your prescriber promptly.
Are there drug interactions with Compounded Semaglutide 3 mg (Sublingual)?: Semaglutide slows gastric emptying and may delay absorption of other oral medications — leave additional time between this preparation and other drugs taken by mouth. Concurrent use with insulin or sulfonylureas increases hypoglycemia risk; dose adjustment of those agents may be necessary. Inform your prescriber of all medications, including thyroid drugs, blood thinners, and over-the-counter preparations.
How should I store Compounded Semaglutide 3 mg (Sublingual)?: Refrigerate at 36°F–46°F (2°C–8°C). Do not freeze. Protect from light. Keep tightly closed. Use within the beyond-use date printed on the pharmacy label. Do not use if the solution appears cloudy, discolored, or contains visible particles.
What precautions should I know about Compounded Semaglutide 3 mg (Sublingual)?: Do not use if you have a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. Notify your prescriber immediately of any severe abdominal pain, persistent nausea, or signs of an allergic reaction. Use only under direct prescriber supervision as part of a comprehensive weight management program. Keep out of reach of children.
Where can I get compounded Compounded Semaglutide 3 mg (Sublingual)?: Compounded Semaglutide 3 mg (Sublingual) is available at compounding pharmacies on the SlimionRX network, including Benbrook pharmacy , Lux Med Compounding Pharmacy.