Methylene Blue Per prescriber order — Compounded Capsule / Oral Solution Patient Monograph

Patient education monograph for Methylene Blue (Per prescriber order), a compounded capsule / oral solution. Learn how it works, how to use it, possible side effects, and find a licensed compounding pharmacy near you.

What is Methylene Blue?

This compounded preparation contains methylene blue formulated pursuant to an individual patient prescription.

How does Methylene Blue work?

Methylene Blue improves mitochondrial electron transport chain efficiency, increasing ATP energy production in neurons. At low doses it may also support memory, focus, and neuroprotection. It additionally has weak MAO inhibitor properties that contribute to its neurological effects.

How to use Methylene Blue

Take as directed by your prescriber. This preparation may cause urine and stools to appear blue-green — this is expected and harmless.

Methylene Blue side effects

Blue-green discoloration of urine and stools is expected and harmless. At higher doses: nausea, vomiting, confusion, rapid heart rate, and elevated blood pressure may occur. Serotonin syndrome is a serious risk when combined with certain drugs.

Drug interactions with Methylene Blue

CRITICAL: Do not combine with SSRIs, SNRIs, MAOIs, triptans, linezolid, or any serotonergic medication — serious serotonin syndrome risk exists. Avoid in G6PD deficiency (risk of hemolytic anemia). Inform all prescribers and pharmacists about this medication.

How to store Methylene Blue

Store at room temperature away from heat and light. Keep tightly closed.

Precautions for Methylene Blue

Do not take if you are currently on serotonergic drugs without prescriber knowledge — serotonin syndrome risk exists. Avoid if you have G6PD deficiency. Keep out of reach of children.

Frequently Asked Questions — Methylene Blue

What is Methylene Blue?
This compounded preparation contains methylene blue formulated pursuant to an individual patient prescription.
How does Methylene Blue work?
Methylene Blue improves mitochondrial electron transport chain efficiency, increasing ATP energy production in neurons. At low doses it may also support memory, focus, and neuroprotection. It additionally has weak MAO inhibitor properties that contribute to its neurological effects.
How do I use Methylene Blue?
Take as directed by your prescriber. This preparation may cause urine and stools to appear blue-green — this is expected and harmless.
What are the side effects of Methylene Blue?
Blue-green discoloration of urine and stools is expected and harmless. At higher doses: nausea, vomiting, confusion, rapid heart rate, and elevated blood pressure may occur. Serotonin syndrome is a serious risk when combined with certain drugs.
Are there drug interactions with Methylene Blue?
CRITICAL: Do not combine with SSRIs, SNRIs, MAOIs, triptans, linezolid, or any serotonergic medication — serious serotonin syndrome risk exists. Avoid in G6PD deficiency (risk of hemolytic anemia). Inform all prescribers and pharmacists about this medication.
How should I store Methylene Blue?
Store at room temperature away from heat and light. Keep tightly closed.
What precautions should I know about Methylene Blue?
Do not take if you are currently on serotonergic drugs without prescriber knowledge — serotonin syndrome risk exists. Avoid if you have G6PD deficiency. Keep out of reach of children.
Where can I get compounded Methylene Blue?
Methylene Blue is available through licensed compounding pharmacies on the SlimionRX network. Visit slimionrx.com to find a pharmacy near you.
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