Ketamine Nasal Spray / Troche Per prescriber order — Compounded Nasal Spray / Troche Patient Monograph

Patient education monograph for Ketamine Nasal Spray / Troche (Per prescriber order), a compounded nasal spray / troche. Learn how it works, how to use it, possible side effects, and find a licensed compounding pharmacy near you.

What is Ketamine Nasal Spray / Troche?

This compounded preparation contains ketamine in a pharmacist-formulated dosage form pursuant to an individual patient prescription for pain management or psychiatric treatment.

How does Ketamine Nasal Spray / Troche work?

Ketamine blocks NMDA (N-methyl-D-aspartate) glutamate receptors in the brain, which are involved in pain signal transmission and depression pathways. At sub-anesthetic doses, it can produce rapid antidepressant effects and reduce central sensitization associated with chronic pain.

How to use Ketamine Nasal Spray / Troche

Use strictly as directed by your prescriber. Ketamine is a controlled substance — do not share or misuse this preparation. Have a responsible adult with you during and after administration.

Ketamine Nasal Spray / Troche side effects

Dissociative effects (feeling detached from your surroundings or body), dizziness, nausea, elevated blood pressure, and perceptual changes (visual or auditory) may occur. These are usually short-lived and dose-dependent. Do not drive after use.

Drug interactions with Ketamine Nasal Spray / Troche

CNS depressants (benzodiazepines, opioids, alcohol) intensify sedation and dissociative effects when combined with ketamine. MAOIs: potentially dangerous interaction. Stimulants may increase cardiovascular effects. Inform all providers about this medication.

How to store Ketamine Nasal Spray / Troche

Store in a secure location at room temperature away from light and heat. Keep locked and out of reach of children.

Precautions for Ketamine Nasal Spray / Troche

This is a Schedule III controlled substance. Do not drive or operate machinery after use. Do not combine with alcohol or other CNS depressants without prescriber guidance.

Frequently Asked Questions — Ketamine Nasal Spray / Troche

What is Ketamine Nasal Spray / Troche?
This compounded preparation contains ketamine in a pharmacist-formulated dosage form pursuant to an individual patient prescription for pain management or psychiatric treatment.
How does Ketamine Nasal Spray / Troche work?
Ketamine blocks NMDA (N-methyl-D-aspartate) glutamate receptors in the brain, which are involved in pain signal transmission and depression pathways. At sub-anesthetic doses, it can produce rapid antidepressant effects and reduce central sensitization associated with chronic pain.
How do I use Ketamine Nasal Spray / Troche?
Use strictly as directed by your prescriber. Ketamine is a controlled substance — do not share or misuse this preparation. Have a responsible adult with you during and after administration.
What are the side effects of Ketamine Nasal Spray / Troche?
Dissociative effects (feeling detached from your surroundings or body), dizziness, nausea, elevated blood pressure, and perceptual changes (visual or auditory) may occur. These are usually short-lived and dose-dependent. Do not drive after use.
Are there drug interactions with Ketamine Nasal Spray / Troche?
CNS depressants (benzodiazepines, opioids, alcohol) intensify sedation and dissociative effects when combined with ketamine. MAOIs: potentially dangerous interaction. Stimulants may increase cardiovascular effects. Inform all providers about this medication.
How should I store Ketamine Nasal Spray / Troche?
Store in a secure location at room temperature away from light and heat. Keep locked and out of reach of children.
What precautions should I know about Ketamine Nasal Spray / Troche?
This is a Schedule III controlled substance. Do not drive or operate machinery after use. Do not combine with alcohol or other CNS depressants without prescriber guidance.
Where can I get compounded Ketamine Nasal Spray / Troche?
Ketamine Nasal Spray / Troche is available through licensed compounding pharmacies on the SlimionRX network. Visit slimionrx.com to find a pharmacy near you.
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